Department of Health and Human Services
National Institutes of Health
National Institute on Aging
Intramural Research Program

The National Institute on Aging (NIA), Intramural Research Program (IRP), a major research component of the National Institutes of Health (NIH) in the Department of Health and Human Services (DHHS), is recruiting a Staff Scientist in the Molecular Neuropathology Unit (MNU) of the Laboratory of Neurogenetics (LNG) in Bethesda, MD. Research at the MNU focuses on understanding the neuropathological and molecular mechanisms of neurodegenerative disorders of the aging population (Parkinson’s Disease, Dementia with Lewy bodies, Multiple system atrophy and Alzheimer’s disease), and developing novel, disease-modifying therapies.

The Staff Scientist will be responsible for designing and performing research in three major related areas: 1) Investigate the molecular mechanisms of neurodegeneration in proteinopathies of the aging population thereby identify novel drug targets for testing in in vitro and in vivo models; 2) Perform comprehensive pre-clinical evaluation of small molecule, immunological, and combinatorial therapeutics in in vivo models of neurodegenerative disorders; and 3) Investigate the interplay between immune responses and mechanisms of neurodegeneration.

The successful individual must have a Ph.D. or equivalent doctoral degree in Biomedical Sciences or related fields, with more than 5 combined years of postdoctoral and working experience in a translational laboratory setting. The individual should be an expert in in vitro and in vivo models of neurodegeneration, synaptic proteins biology, and have substantial authorship in the field of protein aggregation, transmission, neurotoxicity and neuropathology. The individual should have substantial knowledge of drug targets in cutting-edge preclinical neurodegenerative disease models and practical skills to support these efforts.
Staff Scientists do not receive independent resources, although they often work independently and have sophisticated skills and knowledge essential to the work of the Laboratory.

Salary is commensurate with research experience and accomplishments. A full Civil Service package of benefits (including retirement, health, life, and long-term care insurance, Thrift Savings Plan participation, etc.) is available. All employees of the Federal Government are subject to the conflict of interest statutes and regulations, including the Standards of Ethical Conduct. Additional information regarding the NIA IRP is available at the following website:

To apply: Please send a cover letter, curriculum vitae, bibliography, statement of research interests, and three letters of recommendation to: Sarah Lewis, Intramural Program Specialist; Office of the Scientific Director, National Institute on Aging; Vacancy #NIA-IRP-20-15; via email: Applications, including letters of recommendation, must reference the Vacancy #NIA-IRP-20-15. The first round of reviews is expected to occur on or about August 3, 2020; however, applications will be accepted until the position is filled.

DHHS and NIH are Equal Opportunity Employers

The NIH is dedicated to building a diverse community in its training and employment programs.

Type of Opportunity: Permanent Job