Job Description

Vertex Cell and genetic therapies represent two rapidly emerging therapeutic modalities with the potential to treat—and even cure—several of the diseases Vertex is focused on, including sickle cell disease, Duchenne muscular dystrophy and type 1 diabetes. Further investment in a research site specifically designed to advance these programs will be key to Vertex’s continued and sustained leadership in these exciting approaches. At Vertex Cell and Genetic Therapies (VCGT) our research teams will bring together the best biology, technologies and enhanced manufacturing capabilities to ensure we bring these cutting-edge transformative therapies to patients as quickly as possible.

Vertex is seeking talented individuals early in their careers to join our Process Development groups in Boston, Cambridge, MA, and Providence, RI! Our Process Development group offers a fast paced and high energy environment. The successful candidate will be working in cutting edge technologies such as Stem Cell or CRISPR Gene Editing Therapies and will also be responsible for process development, optimization, as well as characterization of cell product for ongoing and future projects.

The candidate will have

– Hands-on experience with cell sorting and enrichment, cell culturing, harvest and cryopreservation.

– Process optimization including scale-up and scale-down models

– Solid background in understanding principles of molecular and cell biology techniques and/or experience working with cell processing devices and bioreactors

– Ability to apply statistical principles to guide process optimization

Key Responsibilities:

Conduct experiments, characterization and data analyses in support of process characterization and improvement
Drive development activities working in a cross-functional environment
Author and review technical reports, regulatory filings, source documents, patents and external publications.
Accountable for troubleshooting and resolving high complex process challenges.
Collaborate within departmental teams, actively contribute to deliverables and engage in team discussion on issue resolution.
For these roles we will either be hiring an early talent individual (0-2 years outside of graduating) with a BS degree into an Associate II role or a MS degree into a Sr. Associate role.

Minimum Requirements:

BS or MS in Pharmaceutical Sciences, Chemical Engineering, Bioengineering
2-5 years of relevant laboratory experience
Hands-on experience working with cell culture
Working knowledge of GxP and working under regulatory environment
Excellent verbal and written communication skills and ability to handle multiple tasks while meeting timelines and adapting to changing priorities.
Strong organizational skills and high attention to details
Flexibility to work (weekend or holidays)
Preferred Qualifications:

Expertise and experience working with stem cell culture (pluripotent or primary hematopoietic stem cell): culturing, sorting, transfection, characterization.
Hands on experience with a variety of techniques such as flow cytometers, sorters, and transfection techniques, including electroporation.
Experience developing processes for clinical applications
Strong background in applying statistical approaches in the design and analysis of experiments and experience with Quality by Design (QbD)

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at

Please note:

December grads should apply before February 8th to be considered for Round 1.
May and/or December grads should apply before March 8th for Round 2 consideration